Obesity and metabolic diseases

Obesity is a condition in which a human has excess body fat. Obesity can increase a person's risk of diseases, health problems, including high blood pressure, diabetes and heart disease. Obesity is mostly caused by a combination of excessive food intake, lack of physical activity, and genetic susceptibility.  A few cases are caused primarily by genes, endocrine disorders, medications and mental disorder. The view that obese people eat little yet gains weight due to a slow metabolism which is not medically supported. Most of the obese people have greater energy expenditure than their normal counterparts due to the energy required to maintain an increased body mass.

 

A metabolic disorder occurs when the metabolism process fails and causes the body to have either too much or too little of the essential substances to stay healthy. Metabolic disorders can take many forms such as a missing enzyme or vitamin that’s necessary for an important chemical reaction, abnormal chemical reactions that hinder metabolic processes and disease in the liver, pancreas, endocrine glands, or other organs involved in metabolism. Metabolic disorders can be present at birth and many can be identified later by routine screening. If a metabolic disorder is not identified early, then it may be diagnosed later in life, when symptoms appear. Specific blood and DNA tests can be done to diagnose genetic metabolic disorders. The gut microbiota, which is a population of microorganisms live in the human digestive system, also has an important part in metabolism and generally has a positive function for its host.